Research

 

The National Center for Nuclear Research, Radioisotope Center POLATOM offers:

  • design of experiments on animals (mice, rats) using radioactive compounds,
  • high standard of housing of animals intended for experiments thanks to appropriately equipped animal houses: conventional cages, individually ventilated cage (IVC) systems and metabolic cages for mice,
  • animals with SPF healthy status are imported from the world’s prestigious breeding centres: Charles River and Janvier Labs,
  • animals with a conventional healthy status are imported from prestigious breeding centres in the world and Poland,
  • groups of experimental animals are selected by age, body weight, sex,
  • specialized apparatus for the study of accumulated radioactivity in the body of animals: scintillation system equipped with a probe for measuring the activity of radionuclides: 99mTc, 131I, 177Lu, 90Y, 68Ga, 18F, 64Cu, 111In, optical imaging apparatus,
  • personnel qualified to carry out the following procedures: organ distribution, subcutaneous induction of cancerous tumours, administration of tested preparations by intravenous, intraperitoneal, intragastric and subcutaneous routes, blood collection,
  • qualified personnel trained in transgenic animal experiments.

All experimental animal housing and laboratory rooms are air-conditioned through a state-of-the-art system to ensure optimal conditions for the maintenance of laboratory animals. Both the animal holding area and the experimental area are under constant monitoring of environmental conditions.

Certificates and Regulations

On 03.11.2011, by Decision No. 7/2011 issued by the Ministry of Science and Higher Education, National Center for Nuclear Research, Radioisotope Center POLATOM was included in the list of experimental units authorized by identification number 0162 to conduct experiments on animals (mice, rats).

On 13.11.2019, by Decision No. 126/2019 issued by the Minister of the Environment, National Center for Nuclear Research, Radioisotope Center POLATOM received permission to operate a genetic engineering facility (No. in the ZIG Register 04-33/2019).

We have a GMP Certificate confirming compliance with the requirements of Good Manufacturing Practice described in Directive 2003/94/EC, concerning control tests (physiological distribution) of radiopharmaceutical products:

  • technetium (99mTc) colloidal tin injection,
  • technetium (99mTc) microspheres injection,
  • technetium (99mTc) succimer injection.

At Radioisotope Center POLATOM, an advisory team for animal welfare was established by Regulation No. 03/2022.